STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa)    
Predicted Functional Partners:
HSD3B7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family.
   
 0.965
CYP27A1
Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.
    
0.948
LOC491379
Aldo_ket_red domain-containing protein.
   
 
 0.833
LOC482711
Aldo_ket_red domain-containing protein.
   
 
 0.833
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 0.812
NR1H4
Nuclear receptor subfamily 1 group H member 4.
   
 0.793
SQLE
Squalene epoxidase.
   
 0.785
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
   
 
 0.761
PTGS2
Prostaglandin-endoperoxide synthase 2.
    
 0.753
PTGES2
Prostaglandin E synthase 2.
     
 0.753
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.