STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HGSNATHeparan-alpha-glucosaminide N-acetyltransferase. (676 aa)    
Predicted Functional Partners:
NAGLU
N-acetyl-alpha-glucosaminidase.
   
 
 0.987
SGSH
N-sulfoglucosamine sulfohydrolase.
   
 
 0.973
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
   
  
 0.874
ARSG
Arylsulfatase G; Displays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate.
   
  
 0.709
IDS
Iduronate 2-sulfatase.
   
  
 0.634
EXTL2
Exostosin like glycosyltransferase 2.
   
  
 0.629
ESCO2
Establishment of sister chromatid cohesion N-acetyltransferase 2.
      
 0.629
IDUA
Alpha-L-iduronidase.
      
 0.615
ESCO1
Establishment of sister chromatid cohesion N-acetyltransferase 1.
      
 0.589
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
  
 0.588
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.