MAP3K10 protein (Canis lupus familiaris) - STRING interaction network

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Score

MAP3K10

Mitogen-activated protein kinase kinase kinase 10. (506 aa)

Predicted Functional Partners:

MAP3K21

0.937

MAP2K7

0.927

HTT

0.897

ENSCAFP00000062410

0.897

MAP3K9

0.881

NCALD

0.792

MAPK8IP2

0.586

TRAF6

0.568

TAB1

0.551

CDC42-2

0.551

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42-2	ENSCAFP00000062410	ENSCAFP00000060180	ENSCAFP00000062410	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.454
CDC42-2	MAP2K7	ENSCAFP00000060180	ENSCAFP00000040122	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Mitogen-activated protein kinase kinase 7.	0.676
CDC42-2	MAP3K10	ENSCAFP00000060180	ENSCAFP00000008036	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Mitogen-activated protein kinase kinase kinase 10.	0.551
CDC42-2	MAP3K21	ENSCAFP00000060180	ENSCAFP00000017003	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Mitogen-activated protein kinase kinase kinase.	0.454
CDC42-2	MAP3K9	ENSCAFP00000060180	ENSCAFP00000024529	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Mitogen-activated protein kinase kinase kinase.	0.454
ENSCAFP00000062410	CDC42-2	ENSCAFP00000062410	ENSCAFP00000060180	Uncharacterized protein; Belongs to the protein kinase superfamily.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.454
ENSCAFP00000062410	HTT	ENSCAFP00000062410	ENSCAFP00000021648	Uncharacterized protein; Belongs to the protein kinase superfamily.	Huntingtin.	0.677
ENSCAFP00000062410	MAP2K7	ENSCAFP00000062410	ENSCAFP00000040122	Uncharacterized protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 7.	0.772
ENSCAFP00000062410	MAP3K10	ENSCAFP00000062410	ENSCAFP00000008036	Uncharacterized protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 10.	0.897
ENSCAFP00000062410	MAP3K21	ENSCAFP00000062410	ENSCAFP00000017003	Uncharacterized protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase.	0.802
ENSCAFP00000062410	MAPK8IP2	ENSCAFP00000062410	ENSCAFP00000000806	Uncharacterized protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase 8 interacting protein 2.	0.586
ENSCAFP00000062410	TAB1	ENSCAFP00000062410	ENSCAFP00000001917	Uncharacterized protein; Belongs to the protein kinase superfamily.	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.516
ENSCAFP00000062410	TRAF6	ENSCAFP00000062410	ENSCAFP00000010159	Uncharacterized protein; Belongs to the protein kinase superfamily.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.483
HTT	ENSCAFP00000062410	ENSCAFP00000021648	ENSCAFP00000062410	Huntingtin.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.677
HTT	MAP3K10	ENSCAFP00000021648	ENSCAFP00000008036	Huntingtin.	Mitogen-activated protein kinase kinase kinase 10.	0.897
HTT	MAP3K21	ENSCAFP00000021648	ENSCAFP00000017003	Huntingtin.	Mitogen-activated protein kinase kinase kinase.	0.635
HTT	MAP3K9	ENSCAFP00000021648	ENSCAFP00000024529	Huntingtin.	Mitogen-activated protein kinase kinase kinase.	0.677
MAP2K7	CDC42-2	ENSCAFP00000040122	ENSCAFP00000060180	Mitogen-activated protein kinase kinase 7.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.676
MAP2K7	ENSCAFP00000062410	ENSCAFP00000040122	ENSCAFP00000062410	Mitogen-activated protein kinase kinase 7.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.772
MAP2K7	MAP3K10	ENSCAFP00000040122	ENSCAFP00000008036	Mitogen-activated protein kinase kinase 7.	Mitogen-activated protein kinase kinase kinase 10.	0.927