STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMTM6CKLF like MARVEL transmembrane domain containing 6. (182 aa)    
Predicted Functional Partners:
CKLF
Chemokine like factor.
      
 0.901
CMTM7
CKLF like MARVEL transmembrane domain containing 7.
   
  
 0.874
CMTM8
CKLF like MARVEL transmembrane domain containing 8.
      
 0.771
CMTM5
CKLF like MARVEL transmembrane domain containing 5.
      
 0.758
CMTM3
CKLF like MARVEL transmembrane domain containing 3.
   
  
 0.752
THRAP3
Thyroid hormone receptor associated protein 3.
   
  
 0.740
INVS
Inversin; Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin- proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does n [...]
    
 
 0.723
CMTM4
CKLF like MARVEL transmembrane domain containing 4.
    
 
0.697
DNAH1
Dynein axonemal heavy chain 1.
      
 0.649
CD151
Tetraspanin.
      
 0.613
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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