STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL35Kelch like family member 35. (579 aa)    
Predicted Functional Partners:
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
   
 
 0.750
HOXC4
Homeobox C4.
   
  
 0.601
ADAM30
ADAM metallopeptidase domain 30.
      
 0.581
KLHL9-2
Uncharacterized protein.
  
  0.570
SCGN
Secretagogin, EF-hand calcium binding protein.
      
 0.563
DEGS2
Delta 4-desaturase, sphingolipid 2.
   
  
 0.554
HSPG2
Heparan sulfate proteoglycan 2.
      
 0.544
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.522
RC3H2
Ring finger and CCCH-type domains 2.
   
 
 0.494
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
   
 
 0.493
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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