STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLR3FProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (775 aa)    
Predicted Functional Partners:
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
   
 0.990
SEC31B
SEC31 homolog B, COPII coat complex component.
   
 0.988
SEC31A
SEC31 homolog A, COPII coat complex component.
   
 0.985
RPL12
60S ribosomal protein L12; Binds directly to 26S ribosomal RNA.
 
    
 0.903
SEC24A
SEC24 homolog A, COPII coat complex component.
   
 
0.900
SEC22B
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
   
 
 0.892
F1PUJ6_CANLF
Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family.
 
    
 0.865
SEC24D
SEC24 homolog D, COPII coat complex component.
   
 
0.845
SAR1B
Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.
   
 
 0.833
SAR1A
Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family.
   
 
 0.809
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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