STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOOK3Hook microtubule tethering protein 3. (755 aa)    
Predicted Functional Partners:
AKTIP
AKT interacting protein.
   
 0.980
FAM160A1
Family with sequence similarity 160 member A1.
    
 
 0.975
FAM160A2
Family with sequence similarity 160 member A2.
    
 
 0.960
BICD2
BICD cargo adaptor 2.
   
 
 0.946
DYNC1LI1
Dynein cytoplasmic 1 light intermediate chain 1.
    
 
 0.868
DCTN1
Dynactin subunit 1.
    
 
 0.823
FAM160B1
Family with sequence similarity 160 member B1.
    
 
 0.805
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
   
 
 0.773
MCM4
DNA helicase; Belongs to the MCM family.
    
 
 0.767
KIF1C
Kinesin family member 1C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.749
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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