STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOOK3Hook microtubule tethering protein 3. (755 aa)    
Predicted Functional Partners:
DYNC1LI1
Dynein cytoplasmic 1 light intermediate chain 1.
   
 
 0.920
AKTIP
AKT interacting protein.
   
 
 0.891
BICD2
BICD cargo adaptor 2.
   
 
 0.859
FAM160B1
Family with sequence similarity 160 member B1.
    
 
 0.856
DYNC1LI2
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 
 0.838
FAM160A2
Family with sequence similarity 160 member A2.
    
 
 0.832
FAM160A1
Family with sequence similarity 160 member A1.
    
 
 0.802
BICDL1
BICD family like cargo adaptor 1.
    
 
 0.738
BICDL2
BICD family like cargo adaptor 2.
    
 
 0.733
CEP120
Centrosomal protein 120.
   
 
 0.682
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.