STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF170Ring finger protein 170. (640 aa)    
Predicted Functional Partners:
ERLIN1
ER lipid raft associated 1.
    
 
 0.945
ERLIN2
ER lipid raft associated 2.
    
 
 0.943
TMUB1
Transmembrane and ubiquitin like domain containing 1.
    
 
 0.908
THAP1
THAP domain containing 1.
 
 
 
 0.849
GPR152
G protein-coupled receptor 152.
    
 
 0.834
PPM1E
Protein phosphatase, Mg2+/Mn2+ dependent 1E.
      
 0.830
SLC25A27
Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.830
TMEM134
Transmembrane protein 134.
      
 0.830
PPP1R26
Protein phosphatase 1 regulatory subunit 26.
      
 0.827
PITPNM1
Phosphatidylinositol transfer protein membrane associated 1.
      
 0.814
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.