| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APOE | C1QA | ENSCAFP00000006888 | ENSCAFP00000040393 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Complement C1q A chain. | 0.733 |
| APOE | C1QB | ENSCAFP00000006888 | ENSCAFP00000039386 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Complement C1q B chain. | 0.544 |
| APOE | C1QC | ENSCAFP00000006888 | ENSCAFP00000021580 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Complement C1q C chain. | 0.456 |
| APOE | LOC475605 | ENSCAFP00000006888 | ENSCAFP00000065293 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Uncharacterized protein. | 0.837 |
| APOE | LPL | ENSCAFP00000006888 | ENSCAFP00000014922 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | 0.952 |
| APOE | LRP1B | ENSCAFP00000006888 | ENSCAFP00000008094 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | LDL receptor related protein 1B. | 0.936 |
| APOE | LRP2 | ENSCAFP00000006888 | ENSCAFP00000017993 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | LDL receptor related protein 2. | 0.942 |
| C1QA | APOE | ENSCAFP00000040393 | ENSCAFP00000006888 | Complement C1q A chain. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.733 |
| C1QA | C1QB | ENSCAFP00000040393 | ENSCAFP00000039386 | Complement C1q A chain. | Complement C1q B chain. | 0.999 |
| C1QA | C1QC | ENSCAFP00000040393 | ENSCAFP00000021580 | Complement C1q A chain. | Complement C1q C chain. | 0.999 |
| C1QA | CALR | ENSCAFP00000040393 | ENSCAFP00000025174 | Complement C1q A chain. | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells. | 0.898 |
| C1QA | LOC475605 | ENSCAFP00000040393 | ENSCAFP00000065293 | Complement C1q A chain. | Uncharacterized protein. | 0.426 |
| C1QA | LRP1B | ENSCAFP00000040393 | ENSCAFP00000008094 | Complement C1q A chain. | LDL receptor related protein 1B. | 0.778 |
| C1QA | LRP2 | ENSCAFP00000040393 | ENSCAFP00000017993 | Complement C1q A chain. | LDL receptor related protein 2. | 0.426 |
| C1QB | APOE | ENSCAFP00000039386 | ENSCAFP00000006888 | Complement C1q B chain. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.544 |
| C1QB | C1QA | ENSCAFP00000039386 | ENSCAFP00000040393 | Complement C1q B chain. | Complement C1q A chain. | 0.999 |
| C1QB | C1QC | ENSCAFP00000039386 | ENSCAFP00000021580 | Complement C1q B chain. | Complement C1q C chain. | 0.999 |
| C1QB | CALR | ENSCAFP00000039386 | ENSCAFP00000025174 | Complement C1q B chain. | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells. | 0.882 |
| C1QB | LOC475605 | ENSCAFP00000039386 | ENSCAFP00000065293 | Complement C1q B chain. | Uncharacterized protein. | 0.404 |
| C1QB | LRP1B | ENSCAFP00000039386 | ENSCAFP00000008094 | Complement C1q B chain. | LDL receptor related protein 1B. | 0.763 |
