STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BANF2Barrier to autointegration factor 2. (90 aa)    
Predicted Functional Partners:
EMD
Emerin.
    
 
 0.805
LMNA
Uncharacterized protein; Belongs to the intermediate filament family.
   
 
 0.758
LMNB1
Lamin B1; Belongs to the intermediate filament family.
   
 
 0.732
LBR
Lamin B receptor.
      
 0.655
HMGA1
High mobility group protein HMG-I/HMG-Y; HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions (By similarity); Belongs to the HMGA family.
    
 
 0.605
LEMD3
LEM domain containing 3.
   
 
 0.573
SCRG1
Stimulator of chondrogenesis 1.
      
 0.560
LMNTD1
Lamin tail domain containing 1.
   
 
 0.546
LMNB2
Lamin B2; Belongs to the intermediate filament family.
   
 
 0.546
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
    
 
 0.525
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.