STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMC1C-X9-C motif containing 1. (283 aa)    
Predicted Functional Partners:
CCDC56
Coiled-coil_56 domain-containing protein.
   
 0.932
SMIM20
Small integral membrane protein 20.
   
 
 0.850
ENSCAFP00000045080
Uncharacterized protein.
    
 0.846
COA1
Cytochrome c oxidase assembly factor 1 homolog.
    
 0.837
SURF1
SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family.
   
 
 0.836
COX17
Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
   
 
 0.784
AZI2
5-azacytidine induced 2.
      
 0.729
E2RA62_CANLF
Coiled-coil_56 domain-containing protein.
   
 
 0.672
CHCHD4
Coiled-coil-helix-coiled-coil-helix domain containing 4.
   
 
 0.589
PUM1
Pumilio RNA binding family member 1.
    
   0.584
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.