STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCSK2Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (638 aa)    
Predicted Functional Partners:
SCG5
Secretogranin V.
   
 
 0.955
SLC30A8
Solute carrier family 30 member 8.
   
  
 0.852
ABCC8
ATP binding cassette subfamily C member 8.
   
 
 0.807
BSND
Barttin CLCNK type accessory beta subunit.
      
 0.797
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.784
PCSK1N
Proprotein convertase subtilisin/kexin type 1 inhibitor.
   
 
 0.770
CPE
Carboxypeptidase E.
   
  
 0.725
LDLR
Low density lipoprotein receptor.
   
  
 0.690
IAPP
Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family.
    
 
 0.685
PTPRN
Protein tyrosine phosphatase receptor type N.
   
  
 0.618
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.