SRGAP3 protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

SRGAP3

SLIT-ROBO Rho GTPase activating protein 3. (1099 aa)

Predicted Functional Partners:

SRGAP1

0.875

ROBO2

0.875

SRGAP2

0.875

ROBO1

0.828

CDC42-2

0.796

WIPF1

0.724

CDC42

0.674

J9NYK5_CANLF

0.674

J9P730_CANLF

0.674

ITSN2

0.625

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	CDC42-2	ENSCAFP00000021684	ENSCAFP00000060180	Cell division cycle 42.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.801
CDC42	ITSN2	ENSCAFP00000021684	ENSCAFP00000006002	Cell division cycle 42.	Intersectin 2.	0.677
CDC42	J9P730_CANLF	ENSCAFP00000021684	ENSCAFP00000041464	Cell division cycle 42.	Uncharacterized protein.	0.801
CDC42	SRGAP1	ENSCAFP00000021684	ENSCAFP00000000489	Cell division cycle 42.	SLIT-ROBO Rho GTPase activating protein 1.	0.733
CDC42	SRGAP2	ENSCAFP00000021684	ENSCAFP00000055135	Cell division cycle 42.	Uncharacterized protein.	0.688
CDC42	SRGAP3	ENSCAFP00000021684	ENSCAFP00000008275	Cell division cycle 42.	SLIT-ROBO Rho GTPase activating protein 3.	0.674
CDC42	WIPF1	ENSCAFP00000021684	ENSCAFP00000019560	Cell division cycle 42.	WAS/WASL interacting protein family member 1.	0.475
CDC42-2	CDC42	ENSCAFP00000060180	ENSCAFP00000021684	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Cell division cycle 42.	0.801
CDC42-2	ITSN2	ENSCAFP00000060180	ENSCAFP00000006002	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Intersectin 2.	0.677
CDC42-2	J9P730_CANLF	ENSCAFP00000060180	ENSCAFP00000041464	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Uncharacterized protein.	0.801
CDC42-2	SRGAP1	ENSCAFP00000060180	ENSCAFP00000000489	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	SLIT-ROBO Rho GTPase activating protein 1.	0.832
CDC42-2	SRGAP2	ENSCAFP00000060180	ENSCAFP00000055135	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Uncharacterized protein.	0.805
CDC42-2	SRGAP3	ENSCAFP00000060180	ENSCAFP00000008275	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	SLIT-ROBO Rho GTPase activating protein 3.	0.796
CDC42-2	WIPF1	ENSCAFP00000060180	ENSCAFP00000019560	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	WAS/WASL interacting protein family member 1.	0.475
ITSN2	CDC42	ENSCAFP00000006002	ENSCAFP00000021684	Intersectin 2.	Cell division cycle 42.	0.677
ITSN2	CDC42-2	ENSCAFP00000006002	ENSCAFP00000060180	Intersectin 2.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.677
ITSN2	J9NYK5_CANLF	ENSCAFP00000006002	ENSCAFP00000038374	Intersectin 2.	Uncharacterized protein.	0.677
ITSN2	J9P730_CANLF	ENSCAFP00000006002	ENSCAFP00000041464	Intersectin 2.	Uncharacterized protein.	0.677
ITSN2	SRGAP1	ENSCAFP00000006002	ENSCAFP00000000489	Intersectin 2.	SLIT-ROBO Rho GTPase activating protein 1.	0.625
ITSN2	SRGAP2	ENSCAFP00000006002	ENSCAFP00000055135	Intersectin 2.	Uncharacterized protein.	0.625