STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYCNSyncollin. (134 aa)    
Predicted Functional Partners:
LOC486100
FAD-binding PCMH-type domain-containing protein.
      
 0.801
RXFP3
Relaxin family peptide receptor 3.
      
 0.759
CLPS
Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
   
  
 0.747
PNLIP
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
  
 0.692
INPP5D
Inositol polyphosphate-5-phosphatase D.
      
 0.687
LOC478196
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
  
 0.676
KLRB1
Killer cell lectin like receptor B1.
   
  
 0.654
GBA
Glucosylceramidase.
      
 0.648
CTRL
Chymotrypsin like; Belongs to the peptidase S1 family.
   
  
 0.619
CCR5
C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).
      
 0.611
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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