FARP1 protein (Canis lupus familiaris) - STRING interaction network

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Score

FARP1

FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1041 aa)

Predicted Functional Partners:

STK24

0.700

CDC42-2

0.665

MYO10

0.609

SDC1

0.593

VMP1

0.591

DCAF12

0.584

NDUFA1

0.570

RAP1B

0.569

RAP1A

0.569

ARHGEF16

0.563

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF16	CDC42-2	ENSCAFP00000039810	ENSCAFP00000060180	Rho guanine nucleotide exchange factor 16.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.602
ARHGEF16	FARP1	ENSCAFP00000039810	ENSCAFP00000008365	Rho guanine nucleotide exchange factor 16.	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	0.563
CDC42-2	ARHGEF16	ENSCAFP00000060180	ENSCAFP00000039810	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rho guanine nucleotide exchange factor 16.	0.602
CDC42-2	FARP1	ENSCAFP00000060180	ENSCAFP00000008365	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	0.665
CDC42-2	MYO10	ENSCAFP00000060180	ENSCAFP00000062247	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.403
CDC42-2	RAP1A	ENSCAFP00000060180	ENSCAFP00000040927	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	RAP1A, member of RAS oncogene family.	0.508
CDC42-2	RAP1B	ENSCAFP00000060180	ENSCAFP00000000596	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	RAP1B, member of RAS oncogene family.	0.517
DCAF12	FARP1	ENSCAFP00000066650	ENSCAFP00000008365	DDB1 and CUL4 associated factor 12.	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	0.584
DCAF12	NDUFA1	ENSCAFP00000066650	ENSCAFP00000056750	DDB1 and CUL4 associated factor 12.	Uncharacterized protein.	0.414
FARP1	ARHGEF16	ENSCAFP00000008365	ENSCAFP00000039810	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Rho guanine nucleotide exchange factor 16.	0.563
FARP1	CDC42-2	ENSCAFP00000008365	ENSCAFP00000060180	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.665
FARP1	DCAF12	ENSCAFP00000008365	ENSCAFP00000066650	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	DDB1 and CUL4 associated factor 12.	0.584
FARP1	MYO10	ENSCAFP00000008365	ENSCAFP00000062247	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.609
FARP1	NDUFA1	ENSCAFP00000008365	ENSCAFP00000056750	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Uncharacterized protein.	0.570
FARP1	RAP1A	ENSCAFP00000008365	ENSCAFP00000040927	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	RAP1A, member of RAS oncogene family.	0.569
FARP1	RAP1B	ENSCAFP00000008365	ENSCAFP00000000596	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	RAP1B, member of RAS oncogene family.	0.569
FARP1	SDC1	ENSCAFP00000008365	ENSCAFP00000059447	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.593
FARP1	STK24	ENSCAFP00000008365	ENSCAFP00000008429	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Serine/threonine kinase 24.	0.700
FARP1	VMP1	ENSCAFP00000008365	ENSCAFP00000026057	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Vacuole membrane protein 1.	0.591
MYO10	CDC42-2	ENSCAFP00000062247	ENSCAFP00000060180	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.403