Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATF6 | CANX | ENSCAFP00000058006 | ENSCAFP00000000498 | Activating transcription factor 6. | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | 0.701 |
| ATF6 | DNAJB11 | ENSCAFP00000058006 | ENSCAFP00000041977 | Activating transcription factor 6. | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | 0.420 |
| ATF6 | DNAJB9 | ENSCAFP00000058006 | ENSCAFP00000059974 | Activating transcription factor 6. | DnaJ heat shock protein family (Hsp40) member B9. | 0.534 |
| ATF6 | EDEM1 | ENSCAFP00000058006 | ENSCAFP00000008377 | Activating transcription factor 6. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.706 |
| ATF6 | OS9 | ENSCAFP00000058006 | ENSCAFP00000000376 | Activating transcription factor 6. | OS9 endoplasmic reticulum lectin. | 0.437 |
| ATF6 | SEL1L | ENSCAFP00000058006 | ENSCAFP00000056064 | Activating transcription factor 6. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.701 |
| ATF6 | XBP1 | ENSCAFP00000058006 | ENSCAFP00000017593 | Activating transcription factor 6. | BZIP domain-containing protein. | 0.954 |
| CANX | ATF6 | ENSCAFP00000000498 | ENSCAFP00000058006 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | Activating transcription factor 6. | 0.701 |
| CANX | EDEM1 | ENSCAFP00000000498 | ENSCAFP00000008377 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.829 |
| CANX | EDEM2 | ENSCAFP00000000498 | ENSCAFP00000011750 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.517 |
| CANX | EDEM3 | ENSCAFP00000000498 | ENSCAFP00000019848 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.552 |
| CANX | OS9 | ENSCAFP00000000498 | ENSCAFP00000000376 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | OS9 endoplasmic reticulum lectin. | 0.538 |
| CANX | SEL1L | ENSCAFP00000000498 | ENSCAFP00000056064 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.604 |
| CANX | XBP1 | ENSCAFP00000000498 | ENSCAFP00000017593 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | BZIP domain-containing protein. | 0.678 |
| DNAJB11 | ATF6 | ENSCAFP00000041977 | ENSCAFP00000058006 | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | Activating transcription factor 6. | 0.420 |
| DNAJB11 | EDEM1 | ENSCAFP00000041977 | ENSCAFP00000008377 | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.796 |
| DNAJB11 | OS9 | ENSCAFP00000041977 | ENSCAFP00000000376 | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | OS9 endoplasmic reticulum lectin. | 0.452 |
| DNAJB11 | XBP1 | ENSCAFP00000041977 | ENSCAFP00000017593 | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | BZIP domain-containing protein. | 0.494 |
| DNAJB9 | ATF6 | ENSCAFP00000059974 | ENSCAFP00000058006 | DnaJ heat shock protein family (Hsp40) member B9. | Activating transcription factor 6. | 0.534 |
| DNAJB9 | EDEM1 | ENSCAFP00000059974 | ENSCAFP00000008377 | DnaJ heat shock protein family (Hsp40) member B9. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.881 |
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