STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF17Rho guanine nucleotide exchange factor 17. (2067 aa)    
Predicted Functional Partners:
NUAK2
NUAK family kinase 2.
      
 0.835
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
      
 0.742
PTPN14
Protein tyrosine phosphatase non-receptor type 14.
   
  
 0.680
AMOTL2
Angiomotin like 2.
    
 
 0.655
RELL1
RELT like 1.
     
  0.600
CRIM1
Cysteine rich transmembrane BMP regulator 1.
   
  
 0.599
TBRG1
Transforming growth factor beta regulator 1.
   
  
 0.588
THSD1
Thrombospondin type 1 domain containing 1.
      
 0.501
TSKU
Tsukushi, small leucine rich proteoglycan.
   
  
 0.499
STING1
Transmembrane protein 173.
   
  0.498
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.