STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
P2RY6Pyrimidinergic receptor P2Y6. (296 aa)    
Predicted Functional Partners:
P2RY2
Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family.
  
 
0.931
GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
   
 0.896
P2RY12
Purinergic receptor P2Y12.
     
 0.893
P2RY1
Purinergic receptor P2Y1 variant 1; Belongs to the G-protein coupled receptor 1 family.
     
0.862
GNA14
G protein subunit alpha 14.
   
 0.832
GNA11
Uncharacterized protein.
   
 0.803
P2RY11
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
     
0.753
CPEB4
Cytoplasmic polyadenylation element binding protein 4.
      
 0.635
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
      
 0.612
PPAN
Brix domain-containing protein.
     
 0.607
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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