STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)    
Predicted Functional Partners:
CASC3
CASC3 exon junction complex subunit.
    
 0.995
RBM8A
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.991
ADIPOQ
Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.
  
0.990
ALYREF
Aly/REF export factor.
   
 0.989
UPF1
UPF1 RNA helicase and ATPase.
   
 0.987
RNPS1
RNA binding protein with serine rich domain 1.
   
 0.987
SRSF3
Serine and arginine rich splicing factor 3.
   
 0.981
CWC22
CWC22 spliceosome associated protein homolog.
   
 0.979
SRSF1
Serine and arginine rich splicing factor 1.
   
 0.975
EIF4A1
Uncharacterized protein; Belongs to the DEAD box helicase family.
  
0.969
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.