STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)    
Predicted Functional Partners:
NOTCH1
Notch receptor 1.
    
0.992
NOTCH3
Notch receptor 3.
   
0.982
NOTCH4
Notch receptor 4.
    
0.979
NOTCH2
Notch receptor 2.
   
0.972
JAG2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.950
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.903
EYS
Uncharacterized protein.
   
 0.886
EYS-2
Uncharacterized protein.
   
 0.886
MIB1
Mindbomb E3 ubiquitin protein ligase 1.
    
 0.830
MAML1
Mastermind like transcriptional coactivator 1.
    
 0.800
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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