SGSH protein (Canis lupus familiaris) - STRING interaction network

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Score

SGSH

N-sulfoglucosamine sulfohydrolase. (507 aa)

Predicted Functional Partners:

HGSNAT

0.972

SUMF1

0.960

IDUA

0.960

NAGLU

0.941

VPS18

0.738

MANBA

0.716

ARSA

0.688

CLCN6

0.676

CLN5

0.648

IDS

0.644

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARSA	IDS	ENSCAFP00000000803	ENSCAFP00000065198	Arylsulfatase A.	Iduronate 2-sulfatase.	0.544
ARSA	IDUA	ENSCAFP00000000803	ENSCAFP00000059514	Arylsulfatase A.	Alpha-L-iduronidase.	0.761
ARSA	NAGLU	ENSCAFP00000000803	ENSCAFP00000022041	Arylsulfatase A.	N-acetyl-alpha-glucosaminidase.	0.480
ARSA	SGSH	ENSCAFP00000000803	ENSCAFP00000008421	Arylsulfatase A.	N-sulfoglucosamine sulfohydrolase.	0.688
ARSA	SUMF1	ENSCAFP00000000803	ENSCAFP00000008923	Arylsulfatase A.	Sulfatase modifying factor 1.	0.848
CLCN6	CLN5	ENSCAFP00000046799	ENSCAFP00000007554	Chloride channel protein.	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	0.802
CLCN6	SGSH	ENSCAFP00000046799	ENSCAFP00000008421	Chloride channel protein.	N-sulfoglucosamine sulfohydrolase.	0.676
CLN5	CLCN6	ENSCAFP00000007554	ENSCAFP00000046799	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Chloride channel protein.	0.802
CLN5	HGSNAT	ENSCAFP00000007554	ENSCAFP00000008021	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	Heparan-alpha-glucosaminide N-acetyltransferase.	0.458
CLN5	NAGLU	ENSCAFP00000007554	ENSCAFP00000022041	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	N-acetyl-alpha-glucosaminidase.	0.408
CLN5	SGSH	ENSCAFP00000007554	ENSCAFP00000008421	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	N-sulfoglucosamine sulfohydrolase.	0.648
HGSNAT	CLN5	ENSCAFP00000008021	ENSCAFP00000007554	Heparan-alpha-glucosaminide N-acetyltransferase.	Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family.	0.458
HGSNAT	IDS	ENSCAFP00000008021	ENSCAFP00000065198	Heparan-alpha-glucosaminide N-acetyltransferase.	Iduronate 2-sulfatase.	0.716
HGSNAT	IDUA	ENSCAFP00000008021	ENSCAFP00000059514	Heparan-alpha-glucosaminide N-acetyltransferase.	Alpha-L-iduronidase.	0.626
HGSNAT	NAGLU	ENSCAFP00000008021	ENSCAFP00000022041	Heparan-alpha-glucosaminide N-acetyltransferase.	N-acetyl-alpha-glucosaminidase.	0.990
HGSNAT	SGSH	ENSCAFP00000008021	ENSCAFP00000008421	Heparan-alpha-glucosaminide N-acetyltransferase.	N-sulfoglucosamine sulfohydrolase.	0.972
HGSNAT	SUMF1	ENSCAFP00000008021	ENSCAFP00000008923	Heparan-alpha-glucosaminide N-acetyltransferase.	Sulfatase modifying factor 1.	0.608
IDS	ARSA	ENSCAFP00000065198	ENSCAFP00000000803	Iduronate 2-sulfatase.	Arylsulfatase A.	0.544
IDS	HGSNAT	ENSCAFP00000065198	ENSCAFP00000008021	Iduronate 2-sulfatase.	Heparan-alpha-glucosaminide N-acetyltransferase.	0.716
IDS	IDUA	ENSCAFP00000065198	ENSCAFP00000059514	Iduronate 2-sulfatase.	Alpha-L-iduronidase.	0.983