STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN12Calpain 12; Belongs to the peptidase C2 family. (594 aa)    
Predicted Functional Partners:
CAPNS1
Calpain small subunit 1.
 
 
0.908
CAST
Calpastatin.
   
 
 0.746
CABP7
Calcium binding protein 7.
   
 
 0.712
RHBDL3
Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
   
 
 0.565
ASB3
Uncharacterized protein.
   
 
 0.534
ANO9
Anoctamin.
   
  
 0.502
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
 
 0.485
SREK1
Splicing regulatory glutamic acid and lysine rich protein 1.
   
  
 0.480
FAS
Fas cell surface death receptor.
   
  
 0.466
RNASEL
Ribonuclease L.
   
 
 0.452
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.