STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAPN12Calpain 12; Belongs to the peptidase C2 family. (594 aa)    
Predicted Functional Partners:
CAPNS1
Calpain small subunit 1.
 
 
0.845
KRT80
Keratin 80; Belongs to the intermediate filament family.
   
  
 0.811
HPS5
Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
      
 0.811
CAST
Calpastatin.
   
 0.776
CAPN11
Calpain 11; Belongs to the peptidase C2 family.
  
 
0.771
KLHL5
Kelch like family member 5.
   
  
 0.720
KRT84
Keratin 84; Belongs to the intermediate filament family.
   
 
 0.716
CAPN9
Calpain 9; Belongs to the peptidase C2 family.
  
 
 
0.693
KRT82
Keratin 82; Belongs to the intermediate filament family.
   
 
 0.679
HIVEP1
Human immunodeficiency virus type I enhancer binding protein 1.
    
 
 0.674
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.