STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF213Ring finger protein 213. (4454 aa)    
Predicted Functional Partners:
LOXHD1
Lipoxygenase homology domains 1.
    
 0.802
NUDCD1
NudC domain containing 1.
    
   0.769
BCL2L14
BCL2 like 14.
   
 
 0.647
PARP14
Poly(ADP-ribose) polymerase family member 14.
   
 
 0.645
EVPL
Envoplakin.
   
 0.614
USP18
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.595
DHX58
DExH-box helicase 58.
   
 
 0.587
SQLE
Squalene epoxidase.
    
 0.561
N4BP1
NEDD4 binding protein 1.
      
 0.549
SLC46A3
Solute carrier family 46 member 3.
      
 0.535
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.