ARAP1 protein (Canis lupus familiaris) - STRING interaction network

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Score

ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1388 aa)

Predicted Functional Partners:

SH3KBP1

0.943

GRB2

0.835

CAPZB

0.731

ASAP1

0.587

CRK

0.587

CDC42-2

0.584

RAP1B

0.540

RAP1A

0.540

PDE2A

0.537

PLEK

0.532

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARAP1	ASAP1	ENSCAFP00000008494	ENSCAFP00000001537	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	0.587
ARAP1	CAPZB	ENSCAFP00000008494	ENSCAFP00000065479	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.731
ARAP1	CDC42-2	ENSCAFP00000008494	ENSCAFP00000060180	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.584
ARAP1	CRK	ENSCAFP00000008494	ENSCAFP00000028257	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	CRK proto-oncogene, adaptor protein.	0.587
ARAP1	GRB2	ENSCAFP00000008494	ENSCAFP00000049390	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Growth factor receptor bound protein 2.	0.835
ARAP1	PDE2A	ENSCAFP00000008494	ENSCAFP00000038297	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Phosphodiesterase.	0.537
ARAP1	PLEK	ENSCAFP00000008494	ENSCAFP00000053827	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Pleckstrin; Major protein kinase C substrate of platelets.	0.532
ARAP1	RAP1A	ENSCAFP00000008494	ENSCAFP00000040927	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	RAP1A, member of RAS oncogene family.	0.540
ARAP1	RAP1B	ENSCAFP00000008494	ENSCAFP00000000596	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	RAP1B, member of RAS oncogene family.	0.540
ARAP1	SH3KBP1	ENSCAFP00000008494	ENSCAFP00000058783	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	SH3 domain containing kinase binding protein 1.	0.943
ASAP1	ARAP1	ENSCAFP00000001537	ENSCAFP00000008494	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	0.587
ASAP1	CRK	ENSCAFP00000001537	ENSCAFP00000028257	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	CRK proto-oncogene, adaptor protein.	0.865
ASAP1	GRB2	ENSCAFP00000001537	ENSCAFP00000049390	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Growth factor receptor bound protein 2.	0.903
ASAP1	PLEK	ENSCAFP00000001537	ENSCAFP00000053827	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	Pleckstrin; Major protein kinase C substrate of platelets.	0.467
ASAP1	SH3KBP1	ENSCAFP00000001537	ENSCAFP00000058783	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.	SH3 domain containing kinase binding protein 1.	0.944
CAPZB	ARAP1	ENSCAFP00000065479	ENSCAFP00000008494	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	0.731
CAPZB	SH3KBP1	ENSCAFP00000065479	ENSCAFP00000058783	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	SH3 domain containing kinase binding protein 1.	0.845
CDC42-2	ARAP1	ENSCAFP00000060180	ENSCAFP00000008494	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	0.584
CDC42-2	CRK	ENSCAFP00000060180	ENSCAFP00000028257	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	CRK proto-oncogene, adaptor protein.	0.475
CDC42-2	GRB2	ENSCAFP00000060180	ENSCAFP00000049390	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Growth factor receptor bound protein 2.	0.650