STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPTX1Neuronal pentraxin 1. (432 aa)    
Predicted Functional Partners:
PPP1R14C
Protein phosphatase 1 regulatory inhibitor subunit 14C.
   
    0.805
CBX6
Chromobox 6.
 
      0.781
E2F1
N-terminal EF-hand calcium binding protein 3.
   
 
 0.755
LRFN1
Leucine rich repeat and fibronectin type III domain containing 1.
   
 
 0.712
DDX11
DEAD/H-box helicase 11.
   
  
 0.670
SLC25A23
Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.651
TMEM25
Transmembrane protein 25.
   
  
 0.642
PLXNA4
Plexin A4.
      
 0.573
FAM171A2
Family with sequence similarity 171 member A2.
   
  
 0.567
ANKRD13B
Ankyrin repeat domain 13B.
      
 0.564
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.