LAMP5 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LAMP5

Lysosomal associated membrane protein family member 5. (280 aa)

Predicted Functional Partners:

P2RX2

0.592

NDNF

0.580

PIEZO2

0.533

CHODL

0.528

SYT6

0.523

CALB2

0.497

UTS2B

0.493

ADARB2

0.485

ADARB1

0.485

SNCG

0.478

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADARB1	LAMP5	ENSCAFP00000016350	ENSCAFP00000008513	Adenosine deaminase RNA specific B1.	Lysosomal associated membrane protein family member 5.	0.485
ADARB2	LAMP5	ENSCAFP00000008248	ENSCAFP00000008513	Adenosine deaminase RNA specific B2 (inactive).	Lysosomal associated membrane protein family member 5.	0.485
CALB2	CHODL	ENSCAFP00000029919	ENSCAFP00000012224	Calbindin 2.	Chondrolectin.	0.493
CALB2	LAMP5	ENSCAFP00000029919	ENSCAFP00000008513	Calbindin 2.	Lysosomal associated membrane protein family member 5.	0.497
CHODL	CALB2	ENSCAFP00000012224	ENSCAFP00000029919	Chondrolectin.	Calbindin 2.	0.493
CHODL	LAMP5	ENSCAFP00000012224	ENSCAFP00000008513	Chondrolectin.	Lysosomal associated membrane protein family member 5.	0.528
LAMP5	ADARB1	ENSCAFP00000008513	ENSCAFP00000016350	Lysosomal associated membrane protein family member 5.	Adenosine deaminase RNA specific B1.	0.485
LAMP5	ADARB2	ENSCAFP00000008513	ENSCAFP00000008248	Lysosomal associated membrane protein family member 5.	Adenosine deaminase RNA specific B2 (inactive).	0.485
LAMP5	CALB2	ENSCAFP00000008513	ENSCAFP00000029919	Lysosomal associated membrane protein family member 5.	Calbindin 2.	0.497
LAMP5	CHODL	ENSCAFP00000008513	ENSCAFP00000012224	Lysosomal associated membrane protein family member 5.	Chondrolectin.	0.528
LAMP5	NDNF	ENSCAFP00000008513	ENSCAFP00000006184	Lysosomal associated membrane protein family member 5.	Neuron derived neurotrophic factor.	0.580
LAMP5	P2RX2	ENSCAFP00000008513	ENSCAFP00000009417	Lysosomal associated membrane protein family member 5.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.592
LAMP5	PIEZO2	ENSCAFP00000008513	ENSCAFP00000027679	Lysosomal associated membrane protein family member 5.	Piezo-type mechanosensitive ion channel component.	0.533
LAMP5	SNCG	ENSCAFP00000008513	ENSCAFP00000060567	Lysosomal associated membrane protein family member 5.	Synuclein gamma; Belongs to the synuclein family.	0.478
LAMP5	SYT6	ENSCAFP00000008513	ENSCAFP00000053284	Lysosomal associated membrane protein family member 5.	Synaptotagmin 6.	0.523
LAMP5	UTS2B	ENSCAFP00000008513	ENSCAFP00000035652	Lysosomal associated membrane protein family member 5.	Urotensin 2B.	0.493
NDNF	LAMP5	ENSCAFP00000006184	ENSCAFP00000008513	Neuron derived neurotrophic factor.	Lysosomal associated membrane protein family member 5.	0.580
NDNF	SNCG	ENSCAFP00000006184	ENSCAFP00000060567	Neuron derived neurotrophic factor.	Synuclein gamma; Belongs to the synuclein family.	0.471
P2RX2	LAMP5	ENSCAFP00000009417	ENSCAFP00000008513	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Lysosomal associated membrane protein family member 5.	0.592
PIEZO2	LAMP5	ENSCAFP00000027679	ENSCAFP00000008513	Piezo-type mechanosensitive ion channel component.	Lysosomal associated membrane protein family member 5.	0.533