MZB1 protein (Canis lupus familiaris) - STRING interaction network

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Score

MZB1

Marginal zone B and B1 cell specific protein. (199 aa)

Predicted Functional Partners:

TNFRSF17

0.986

JCHAIN

0.952

POU2AF1

0.944

MS4A1

0.778

SLC23A1

0.705

LOC482707

0.698

CD79A

0.693

CD3D

0.655

CD79B

0.624

VPREB3

0.608

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD3D	CD79A	ENSCAFP00000038117	ENSCAFP00000053606	CD3d molecule.	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	0.846
CD3D	CD79B	ENSCAFP00000038117	ENSCAFP00000018654	CD3d molecule.	CD79b molecule.	0.729
CD3D	JCHAIN	ENSCAFP00000038117	ENSCAFP00000035905	CD3d molecule.	Joining chain of multimeric IgA and IgM.	0.548
CD3D	MS4A1	ENSCAFP00000038117	ENSCAFP00000035044	CD3d molecule.	B-lymphocyte antigen CD20; B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.	0.840
CD3D	MZB1	ENSCAFP00000038117	ENSCAFP00000008517	CD3d molecule.	Marginal zone B and B1 cell specific protein.	0.655
CD79A	CD3D	ENSCAFP00000053606	ENSCAFP00000038117	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	CD3d molecule.	0.846
CD79A	CD79B	ENSCAFP00000053606	ENSCAFP00000018654	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	CD79b molecule.	0.999
CD79A	JCHAIN	ENSCAFP00000053606	ENSCAFP00000035905	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	Joining chain of multimeric IgA and IgM.	0.796
CD79A	MS4A1	ENSCAFP00000053606	ENSCAFP00000035044	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	B-lymphocyte antigen CD20; B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.	0.978
CD79A	MZB1	ENSCAFP00000053606	ENSCAFP00000008517	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	Marginal zone B and B1 cell specific protein.	0.693
CD79A	POU2AF1	ENSCAFP00000053606	ENSCAFP00000062886	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	POU class 2 homeobox associating factor 1.	0.769
CD79A	TNFRSF17	ENSCAFP00000053606	ENSCAFP00000037981	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	TNF receptor superfamily member 17.	0.535
CD79A	VPREB3	ENSCAFP00000053606	ENSCAFP00000020819	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	V-set pre-B cell surrogate light chain 3.	0.933
CD79B	CD3D	ENSCAFP00000018654	ENSCAFP00000038117	CD79b molecule.	CD3d molecule.	0.729
CD79B	CD79A	ENSCAFP00000018654	ENSCAFP00000053606	CD79b molecule.	B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]	0.999
CD79B	JCHAIN	ENSCAFP00000018654	ENSCAFP00000035905	CD79b molecule.	Joining chain of multimeric IgA and IgM.	0.798
CD79B	MS4A1	ENSCAFP00000018654	ENSCAFP00000035044	CD79b molecule.	B-lymphocyte antigen CD20; B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.	0.878
CD79B	MZB1	ENSCAFP00000018654	ENSCAFP00000008517	CD79b molecule.	Marginal zone B and B1 cell specific protein.	0.624
CD79B	POU2AF1	ENSCAFP00000018654	ENSCAFP00000062886	CD79b molecule.	POU class 2 homeobox associating factor 1.	0.809
CD79B	VPREB3	ENSCAFP00000018654	ENSCAFP00000020819	CD79b molecule.	V-set pre-B cell surrogate light chain 3.	0.905