STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP131Centrosomal protein 131. (1000 aa)    
Predicted Functional Partners:
PCM1
Pericentriolar material 1.
   
 
 0.850
PLK1
Serine/threonine-protein kinase PLK.
    
 0.830
NIN
Ninein.
    
 
 0.803
MKRN2
Makorin ring finger protein 2.
    
 
 0.734
CEP72
Centrosomal protein 72.
    
 
 0.688
CEP290
Centrosomal protein 290.
   
 
 0.679
BBS4
Ariadne RBR E3 ubiquitin protein ligase 1.
   
 
 0.671
MAP1S
Microtubule associated protein 1S.
   
 
 0.658
PDZD4
PDZ domain containing 4.
    
 
 0.655
CCDC66
Coiled-coil domain-containing protein 66; Microtubule-binding protein required for ciliogenesis. May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites (By similarity). Plays a role in retina morphogenesis and/or homeostasis.
    
 
 0.651
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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