STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YIPF4Protein YIPF. (244 aa)    
Predicted Functional Partners:
YIPF3
Yip1 domain family member 3.
   
 
 0.941
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein.
   
 
 0.792
YIPF2
Yip1 domain family member 2.
   
 
 0.754
YIPF1
Protein YIPF.
   
 
 0.748
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein.
   
 
 0.712
IER3IP1
Uncharacterized protein.
   
 
 0.626
SNX16
Sorting nexin 16.
      
 0.534
CD8A
T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...]
      
 0.525
SLC66A3
Solute carrier family 66 member 3.
      
 0.520
TIRAP
TIR domain containing adaptor protein.
      
 0.490
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.