STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYT1Synaptotagmin 1. (422 aa)    
Predicted Functional Partners:
SNAP25
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 
 0.939
VAMP2
V-SNARE coiled-coil homology domain-containing protein.
   
 
 0.899
VAMP1
Vesicle associated membrane protein 1.
   
 
 0.853
STX1A
Syntaxin 1A; Belongs to the syntaxin family.
   
 
 0.850
STON2
Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.
   
 
 0.821
STX1B
Syntaxin 1B; Belongs to the syntaxin family.
   
 
 0.781
VAMP3
Vesicle associated membrane protein 3.
    
 
 0.781
SYT5
Synaptotagmin 5.
   
   0.722
STX3
Syntaxin 3; Belongs to the syntaxin family.
   
 
 0.691
RAB3C
RAB3C, member RAS oncogene family.
   
 
 0.685
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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