STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (1015 aa)    
Predicted Functional Partners:
STAM
Signal transducing adaptor molecule.
   
0.998
STAM2
Signal transducing adaptor molecule 2.
   
0.994
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 0.934
TSG101
Tumor susceptibility 101.
    
 
 0.929
ENSCAFP00000045211
SB domain-containing protein.
    
 
 0.929
UBB
Ubiquitin B.
   
 0.908
EGFR
Receptor protein-tyrosine kinase.
    
 0.904
USP8
Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.
   
 0.873
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.863
ENSCAFP00000050780
Ubiquitin-like domain-containing protein.
    
 0.863
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.