BIRC6 protein (Canis lupus familiaris) - STRING interaction network

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BIRC6

Baculoviral IAP repeat containing 6. (4778 aa)

Predicted Functional Partners:

HTRA2

0.960

RNF41

0.929

GABARAPL2

0.919

MAP1LC3C

0.914

UBA6

0.907

CASP9

0.896

DIABLO

0.895

CASP7

0.892

HECTD1

0.877

CASP3

0.869

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC6	CASP3	ENSCAFP00000008679	ENSCAFP00000011475	Baculoviral IAP repeat containing 6.	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	0.869
BIRC6	CASP7	ENSCAFP00000008679	ENSCAFP00000016420	Baculoviral IAP repeat containing 6.	Caspase 7; Belongs to the peptidase C14A family.	0.892
BIRC6	CASP9	ENSCAFP00000008679	ENSCAFP00000063413	Baculoviral IAP repeat containing 6.	Caspase 9; Belongs to the peptidase C14A family.	0.896
BIRC6	DIABLO	ENSCAFP00000008679	ENSCAFP00000011742	Baculoviral IAP repeat containing 6.	Diablo IAP-binding mitochondrial protein.	0.895
BIRC6	GABARAPL2	ENSCAFP00000008679	ENSCAFP00000039909	Baculoviral IAP repeat containing 6.	GABA type A receptor associated protein like 2.	0.919
BIRC6	HECTD1	ENSCAFP00000008679	ENSCAFP00000019037	Baculoviral IAP repeat containing 6.	HECT domain E3 ubiquitin protein ligase 1.	0.877
BIRC6	HTRA2	ENSCAFP00000008679	ENSCAFP00000012325	Baculoviral IAP repeat containing 6.	Protease serine 25.	0.960
BIRC6	MAP1LC3C	ENSCAFP00000008679	ENSCAFP00000041897	Baculoviral IAP repeat containing 6.	Microtubule associated protein 1 light chain 3 gamma.	0.914
BIRC6	RNF41	ENSCAFP00000008679	ENSCAFP00000000162	Baculoviral IAP repeat containing 6.	Ring finger protein 41.	0.929
BIRC6	UBA6	ENSCAFP00000008679	ENSCAFP00000004058	Baculoviral IAP repeat containing 6.	Ubiquitin like modifier activating enzyme 6.	0.907
CASP3	BIRC6	ENSCAFP00000011475	ENSCAFP00000008679	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Baculoviral IAP repeat containing 6.	0.869
CASP3	CASP7	ENSCAFP00000011475	ENSCAFP00000016420	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Caspase 7; Belongs to the peptidase C14A family.	0.928
CASP3	CASP9	ENSCAFP00000011475	ENSCAFP00000063413	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.997
CASP3	DIABLO	ENSCAFP00000011475	ENSCAFP00000011742	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Diablo IAP-binding mitochondrial protein.	0.517
CASP3	HTRA2	ENSCAFP00000011475	ENSCAFP00000012325	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Protease serine 25.	0.528
CASP7	BIRC6	ENSCAFP00000016420	ENSCAFP00000008679	Caspase 7; Belongs to the peptidase C14A family.	Baculoviral IAP repeat containing 6.	0.892
CASP7	CASP3	ENSCAFP00000016420	ENSCAFP00000011475	Caspase 7; Belongs to the peptidase C14A family.	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	0.928
CASP7	CASP9	ENSCAFP00000016420	ENSCAFP00000063413	Caspase 7; Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.974
CASP7	DIABLO	ENSCAFP00000016420	ENSCAFP00000011742	Caspase 7; Belongs to the peptidase C14A family.	Diablo IAP-binding mitochondrial protein.	0.427
CASP9	BIRC6	ENSCAFP00000063413	ENSCAFP00000008679	Caspase 9; Belongs to the peptidase C14A family.	Baculoviral IAP repeat containing 6.	0.896