STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKHD1ANK_REP_REGION domain-containing protein. (2650 aa)    
Predicted Functional Partners:
CNTF
Uncharacterized protein.
   
 0.818
FGF8
Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells (By similarity).
    
   0.780
PRRC2C
Proline rich coiled-coil 2C.
   
 
 0.754
CGAS
Cyclic GMP-AMP synthase.
    
 
 0.719
FPGT
Fucose-1-phosphate guanylyltransferase.
    
 0.713
HHLA1
HERV-H LTR-associating 1.
    
 0.650
MX1
Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).
    
 0.648
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
    
 
 0.631
PRRC2A
Proline rich coiled-coil 2A.
   
 
 0.625
USP34
Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family.
   
 
 0.612
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.