| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALS2 | RAB5A | ENSCAFP00000018218 | ENSCAFP00000008690 | Alsin Rho guanine nucleotide exchange factor ALS2. | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | 0.957 |
| ALS2 | RAB5C | ENSCAFP00000018218 | ENSCAFP00000022977 | Alsin Rho guanine nucleotide exchange factor ALS2. | Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.854 |
| ALS2 | RABGEF1 | ENSCAFP00000018218 | ENSCAFP00000015865 | Alsin Rho guanine nucleotide exchange factor ALS2. | RAB guanine nucleotide exchange factor 1. | 0.631 |
| EEA1 | PIK3C3 | ENSCAFP00000009251 | ENSCAFP00000026166 | Early endosome antigen 1. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.928 |
| EEA1 | RAB5A | ENSCAFP00000009251 | ENSCAFP00000008690 | Early endosome antigen 1. | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | 0.949 |
| EEA1 | RAB5C | ENSCAFP00000009251 | ENSCAFP00000022977 | Early endosome antigen 1. | Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.932 |
| EEA1 | VPS18 | ENSCAFP00000009251 | ENSCAFP00000054950 | Early endosome antigen 1. | VPS18 core subunit of CORVET and HOPS complexes. | 0.497 |
| PIK3C3 | EEA1 | ENSCAFP00000026166 | ENSCAFP00000009251 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Early endosome antigen 1. | 0.928 |
| PIK3C3 | RAB5A | ENSCAFP00000026166 | ENSCAFP00000008690 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | 0.958 |
| PIK3C3 | RAB5C | ENSCAFP00000026166 | ENSCAFP00000022977 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.963 |
| PIK3C3 | RBSN | ENSCAFP00000026166 | ENSCAFP00000056036 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Rabenosyn, RAB effector. | 0.680 |
| PIK3C3 | TGFBRAP1 | ENSCAFP00000026166 | ENSCAFP00000003101 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Transforming growth factor beta receptor associated protein 1. | 0.430 |
| PIK3C3 | VPS11 | ENSCAFP00000026166 | ENSCAFP00000018221 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.585 |
| PIK3C3 | VPS16 | ENSCAFP00000026166 | ENSCAFP00000009824 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.409 |
| PIK3C3 | VPS18 | ENSCAFP00000026166 | ENSCAFP00000054950 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | VPS18 core subunit of CORVET and HOPS complexes. | 0.530 |
| RAB5A | ALS2 | ENSCAFP00000008690 | ENSCAFP00000018218 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Alsin Rho guanine nucleotide exchange factor ALS2. | 0.957 |
| RAB5A | EEA1 | ENSCAFP00000008690 | ENSCAFP00000009251 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Early endosome antigen 1. | 0.949 |
| RAB5A | PIK3C3 | ENSCAFP00000008690 | ENSCAFP00000026166 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.958 |
| RAB5A | RAB5C | ENSCAFP00000008690 | ENSCAFP00000022977 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.937 |
| RAB5A | RABGEF1 | ENSCAFP00000008690 | ENSCAFP00000015865 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | RAB guanine nucleotide exchange factor 1. | 0.981 |
