Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM32ADAM metallopeptidase domain 32. (767 aa)    
Predicted Functional Partners:
IZUMO2
IZUMO family member 2.
   
  
 0.710
IZUMO3
IZUMO family member 3.
   
  
 0.703
IZUMO4
IZUMO family member 4.
   
  
 0.500
SPATA21
Spermatogenesis associated 21.
      
 0.469
PLEKHA2
Pleckstrin homology domain containing A2.
    
 
 0.469
IQCG
IQ motif containing G.
      
 0.467
ADAM10
ADAM metallopeptidase domain 10.
     
0.417
TEX55
Testis expressed 55.
   
  
 0.411
ATXN2L
Ataxin 2 like.
      
 0.408
AMER3
APC membrane recruitment protein 3.
      
 0.402
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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