STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCCAPropionyl-CoA carboxylase subunit alpha. (731 aa)    
Predicted Functional Partners:
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
 
 0.999
PCCB
Propionyl-CoA carboxylase subunit beta.
 
 0.999
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
  
0.959
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.943
ACADS
Acyl-CoA dehydrogenase short chain.
  
 
 0.941
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.934
MCEE
Methylmalonyl-CoA epimerase.
  
 
 0.932
ALDH9A1
Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family.
   
 
 0.932
ACAA2
Thiolase_N domain-containing protein.
  
 0.928
HLCS
Holocarboxylase synthetase.
    
 0.922
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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