STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTN4Actinin alpha 4. (1163 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.976
CTNNA3
Catenin alpha 3.
   
 0.946
CTNNA2
Catenin alpha 2.
   
 0.946
CTNNA1
Catenin alpha 1.
   
 0.944
ZYX
Zyxin.
   
 0.940
LMO7
LIM domain 7.
    
 0.937
ACTN1
Actinin alpha 1.
  
 
0.932
SSX2IP
SSX family member 2 interacting protein.
   
 0.910
PIP5K1A
PIPK domain-containing protein.
   
 
 0.905
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
   
 
 0.904
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.