STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACTN4Actinin alpha 4. (1163 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.987
ZYX
Zyxin.
   
 0.952
CTNNA3
Catenin alpha 3.
   
 0.940
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
   
 
 0.924
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 0.920
LMO7
LIM domain 7.
   
 0.909
SSX2IP
SSX family member 2 interacting protein.
    
 0.898
ACTN1
Actinin alpha 1.
   
 
  0.891
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.890
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
   
 
 0.888
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.