STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMCO6Transmembrane and coiled-coil domains 6. (499 aa)    
Predicted Functional Partners:
ZNF511
Zinc finger protein 511.
    
   0.926
E2QZ56_CANLF
Uncharacterized protein.
    
 
 0.689
LSM5
U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.
    
 
 0.689
CSE1L
Chromosome segregation 1 like.
   
 0.592
LSM7
Sm domain-containing protein.
    
   0.566
LSM6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated.
    
   0.553
LSM4
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
   0.489
LSM4-2
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
   0.489
KPNB1
Karyopherin subunit beta 1.
   
 
 0.474
PHYHIPL
Phytanoyl-CoA 2-hydroxylase interacting protein like.
    
 
 0.461
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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