STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRIM1Cysteine rich transmembrane BMP regulator 1. (1037 aa)    
Predicted Functional Partners:
GIPC2
GIPC PDZ domain containing family member 2.
   
  
 0.742
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.689
ENSCAFP00000054759
Ubiquitin-like domain-containing protein.
   
 
 0.689
ENSCAFP00000061156
Ubiquitin-like domain-containing protein.
   
 
 0.689
KCTD9
Potassium channel tetramerization domain containing 9.
   
  
 0.651
NUAK2
NUAK family kinase 2.
   
  
 0.649
HOXA1
Homeobox A1.
   
  
 0.648
ZNF71
Zinc finger protein 71.
    
 
 0.646
CDC42EP2
Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.
      
 0.617
ARHGEF17
Rho guanine nucleotide exchange factor 17.
   
  
 0.586
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.