Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HAO1Hydroxyacid oxidase 1. (370 aa)    
Predicted Functional Partners:
DAO
D-amino acid oxidase.
   
 
 0.977
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.
   
 
 0.954
HAO2
Hydroxyacid oxidase 2.
  
 
0.954
LOC607355
Aminotran_5 domain-containing protein.
  
 0.949
GRHPR
Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.936
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.921
PIPOX
Pipecolic acid and sarcosine oxidase.
   
 
 0.908
LOC100855679
Aminotran_5 domain-containing protein.
  
 0.903
F6XEV4_CANLF
Uncharacterized protein.
   
 
 0.900
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
   
 
 0.870
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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