STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HARS1Histidyl-tRNA synthetase. (509 aa)    
Predicted Functional Partners:
HARS2
Histidyl-tRNA synthetase 2, mitochondrial.
   
  0.966
YARS1
Tyrosine--tRNA ligase.
  
 
 0.861
ALG11
ALG11 alpha-1,2-mannosyltransferase.
   
  
 0.795
TGDS
TDP-glucose 4,6-dehydratase.
      
 0.777
EPRS1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.759
MARS1
Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.715
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.686
VARS1
Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.641
RARS1
Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.633
PSMD14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.632
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.