STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HARS2Histidyl-tRNA synthetase 2, mitochondrial. (511 aa)    
Predicted Functional Partners:
HARS1
Histidyl-tRNA synthetase.
   
  0.966
ENSCAFP00000051589
WHEP-TRS domain-containing protein.
   
  0.966
ENSCAFP00000053634
tRNA-synt_His domain-containing protein.
   
  0.966
LARS2
Leucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.908
ERAL1
Era like 12S mitochondrial rRNA chaperone 1.
  
  
 0.895
YARS1
Tyrosine--tRNA ligase.
  
 
 0.861
HSD17B4
Hydroxysteroid 17-beta dehydrogenase 4.
   
  
 0.784
CLPP
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.779
EPRS1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.759
MARS1
Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.733
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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