PSMD8 protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

PSMD8

Proteasome 26S subunit, non-ATPase 8. (455 aa)

Predicted Functional Partners:

NF1

0.825

SPRED1

0.802

STAM

0.795

STAM2

0.746

CNTFR

0.592

SOCS5

0.592

PSMB3

0.581

PSMD2

0.555

SMIM3

0.553

NRAS

0.548

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTFR	PSMD8	ENSCAFP00000002838	ENSCAFP00000008867	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Proteasome 26S subunit, non-ATPase 8.	0.592
CNTFR	STAM	ENSCAFP00000002838	ENSCAFP00000006746	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Signal transducing adaptor molecule.	0.464
CNTFR	STAM2	ENSCAFP00000002838	ENSCAFP00000008664	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Signal transducing adaptor molecule 2.	0.425
NF1	NRAS	ENSCAFP00000035952	ENSCAFP00000014016	Neurofibromin 1.	Uncharacterized protein.	0.982
NF1	PSMB3	ENSCAFP00000035952	ENSCAFP00000024397	Neurofibromin 1.	Proteasome subunit beta.	0.400
NF1	PSMD2	ENSCAFP00000035952	ENSCAFP00000018645	Neurofibromin 1.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.435
NF1	PSMD8	ENSCAFP00000035952	ENSCAFP00000008867	Neurofibromin 1.	Proteasome 26S subunit, non-ATPase 8.	0.825
NF1	SPRED1	ENSCAFP00000035952	ENSCAFP00000047550	Neurofibromin 1.	Sprouty related EVH1 domain containing 1.	0.968
NRAS	NF1	ENSCAFP00000014016	ENSCAFP00000035952	Uncharacterized protein.	Neurofibromin 1.	0.982
NRAS	PSMD8	ENSCAFP00000014016	ENSCAFP00000008867	Uncharacterized protein.	Proteasome 26S subunit, non-ATPase 8.	0.548
NRAS	SPRED1	ENSCAFP00000014016	ENSCAFP00000047550	Uncharacterized protein.	Sprouty related EVH1 domain containing 1.	0.781
PSMB3	NF1	ENSCAFP00000024397	ENSCAFP00000035952	Proteasome subunit beta.	Neurofibromin 1.	0.400
PSMB3	PSMD2	ENSCAFP00000024397	ENSCAFP00000018645	Proteasome subunit beta.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.935
PSMB3	PSMD8	ENSCAFP00000024397	ENSCAFP00000008867	Proteasome subunit beta.	Proteasome 26S subunit, non-ATPase 8.	0.581
PSMB3	SPRED1	ENSCAFP00000024397	ENSCAFP00000047550	Proteasome subunit beta.	Sprouty related EVH1 domain containing 1.	0.400
PSMD2	NF1	ENSCAFP00000018645	ENSCAFP00000035952	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Neurofibromin 1.	0.435
PSMD2	PSMB3	ENSCAFP00000018645	ENSCAFP00000024397	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Proteasome subunit beta.	0.935
PSMD2	PSMD8	ENSCAFP00000018645	ENSCAFP00000008867	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Proteasome 26S subunit, non-ATPase 8.	0.555
PSMD2	SPRED1	ENSCAFP00000018645	ENSCAFP00000047550	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Sprouty related EVH1 domain containing 1.	0.597
PSMD8	CNTFR	ENSCAFP00000008867	ENSCAFP00000002838	Proteasome 26S subunit, non-ATPase 8.	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	0.592