STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAC3Uncharacterized protein. (210 aa)    
Predicted Functional Partners:
NCKAP1
NCK associated protein 1.
    
 0.917
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.917
PREX1
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1.
    
 0.917
CYBA
Cytochrome b-245 alpha chain.
   
 0.915
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 0.910
PAK2
Non-specific serine/threonine protein kinase.
   
 0.910
BAIAP2
BAI1 associated protein 2.
    
 0.909
NCF4
Neutrophil cytosolic factor 4.
   
 0.900
VAV2
Vav guanine nucleotide exchange factor 2.
    
 0.896
PAK6
Non-specific serine/threonine protein kinase.
   
 0.893
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.