STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAC3Uncharacterized protein. (210 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 0.961
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.959
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.957
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
   
 0.953
NCKAP1
NCK associated protein 1.
   
 0.953
DOCK2
Dedicator of cytokinesis 2; Belongs to the DOCK family.
   
 0.953
PAK1
Non-specific serine/threonine protein kinase.
   
 0.953
PLXNB1
Plexin B1.
   
 0.952
PLXNB3
Plexin B3.
   
 0.952
PAK3
P21 (RAC1) activated kinase 3.
   
 0.947
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.