Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ANKRD28Ankyrin repeat domain 28. (1083 aa)    
Predicted Functional Partners:
PPP6R1
Protein phosphatase 6 regulatory subunit 1.
   
 0.972
PPP6R3
Protein phosphatase 6 regulatory subunit 3.
   
 0.934
PPP6C
Serine/threonine-protein phosphatase.
    
 0.831
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
    
 
 0.816
MOB1B
MOB kinase activator 1B.
    
 0.733
PPP6R2
Protein phosphatase 6 regulatory subunit 2.
   
 
 0.725
CRLF3
Cytokine receptor like factor 3.
   
  
 0.698
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
   0.684
PPP6C-2
Protein phosphatase 6 catalytic subunit.
    
 0.677
NEK2
NIMA related kinase 2.
    
 0.639
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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