STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FERMT1Fermitin family member 1. (695 aa)    
Predicted Functional Partners:
ILK
Integrin linked kinase.
   
 
 0.908
KLHL24
Kelch like family member 24.
    
 
 0.735
PKP1
Uncharacterized protein.
   
 
 0.718
COL17A1
120 kDa linear IgA disease antigen homolog; The 120 kDa linear IgA disease antigen homolog is an anchoring filament component involved in dermal-epidermal cohesion.
   
  
 0.711
LPXN
Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN).
   
 
 0.670
COL7A1
Collagen type VII alpha 1 chain.
   
  
 0.649
EXPH5
Exophilin 5.
   
  
 0.648
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.609
LAMB3
Laminin subunit beta 3.
   
  
 0.609
FERMT3
Fermitin family member 3.
  
 
 
0.600
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.