SPINT2 protein (Canis lupus familiaris) - STRING interaction network

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Score

SPINT2

Uncharacterized protein. (252 aa)

Predicted Functional Partners:

HGF

0.824

MST1

0.810

STAC2

0.791

LOC475521

0.784

WFDC8

0.774

PRSS2

0.757

SPINT4

0.692

VCAM1

0.670

SLC44A4

0.627

EPCAM

0.621

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPCAM	SPINT2	ENSCAFP00000003865	ENSCAFP00000008919	Epithelial cell adhesion molecule.	Uncharacterized protein.	0.621
HGF	SPINT2	ENSCAFP00000009539	ENSCAFP00000008919	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.824
HGF	VCAM1	ENSCAFP00000009539	ENSCAFP00000029643	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	Vascular cell adhesion protein 1; Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation (By similarity).	0.457
LOC475521	SPINT2	ENSCAFP00000005682	ENSCAFP00000008919	Cationic trypsin.	Uncharacterized protein.	0.784
LOC475521	SPINT4	ENSCAFP00000005682	ENSCAFP00000014284	Cationic trypsin.	Serine peptidase inhibitor, Kunitz type 4.	0.557
LOC475521	WFDC8	ENSCAFP00000005682	ENSCAFP00000014256	Cationic trypsin.	WAP four-disulfide core domain 8.	0.613
MST1	SPINT2	ENSCAFP00000016787	ENSCAFP00000008919	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.810
PRSS2	SPINT2	ENSCAFP00000043963	ENSCAFP00000008919	Anionic trypsin.	Uncharacterized protein.	0.757
PRSS2	SPINT4	ENSCAFP00000043963	ENSCAFP00000014284	Anionic trypsin.	Serine peptidase inhibitor, Kunitz type 4.	0.516
PRSS2	WFDC8	ENSCAFP00000043963	ENSCAFP00000014256	Anionic trypsin.	WAP four-disulfide core domain 8.	0.559
SLC44A4	SPINT2	ENSCAFP00000000938	ENSCAFP00000008919	Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family.	Uncharacterized protein.	0.627
SPINT2	EPCAM	ENSCAFP00000008919	ENSCAFP00000003865	Uncharacterized protein.	Epithelial cell adhesion molecule.	0.621
SPINT2	HGF	ENSCAFP00000008919	ENSCAFP00000009539	Uncharacterized protein.	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	0.824
SPINT2	LOC475521	ENSCAFP00000008919	ENSCAFP00000005682	Uncharacterized protein.	Cationic trypsin.	0.784
SPINT2	MST1	ENSCAFP00000008919	ENSCAFP00000016787	Uncharacterized protein.	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.810
SPINT2	PRSS2	ENSCAFP00000008919	ENSCAFP00000043963	Uncharacterized protein.	Anionic trypsin.	0.757
SPINT2	SLC44A4	ENSCAFP00000008919	ENSCAFP00000000938	Uncharacterized protein.	Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family.	0.627
SPINT2	SPINT4	ENSCAFP00000008919	ENSCAFP00000014284	Uncharacterized protein.	Serine peptidase inhibitor, Kunitz type 4.	0.692
SPINT2	STAC2	ENSCAFP00000008919	ENSCAFP00000024254	Uncharacterized protein.	SH3 and cysteine rich domain 2.	0.791
SPINT2	VCAM1	ENSCAFP00000008919	ENSCAFP00000029643	Uncharacterized protein.	Vascular cell adhesion protein 1; Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation (By similarity).	0.670