STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRN1Leucine rich repeat neuronal 1. (716 aa)    
Predicted Functional Partners:
SETMAR
Uncharacterized protein.
    
 
 0.596
SYNC
Syncoilin, intermediate filament protein; Belongs to the intermediate filament family.
   
 0.556
NTNG1
Netrin G1.
    
 0.467
CACHD1
Cache domain containing 1.
     
 0.463
SUMF1
Sulfatase modifying factor 1.
    
 0.439
LRRC1
Leucine rich repeat containing 1.
  
   
 0.438
E2RBZ7_CANLF
Uncharacterized protein.
    
  0.426
CRBN
Cereblon.
      
 0.423
ADAM22
ADAM metallopeptidase domain 22.
   
 
 0.423
ADAM23
ADAM metallopeptidase domain 23.
    
 
 0.411
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.