STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2R8N3_CANLFUncharacterized protein. (1137 aa)    
Predicted Functional Partners:
ENSCAFP00000052013
Uncharacterized protein.
 
      0.899
MYB
MYB proto-oncogene, transcription factor.
      
 0.515
DENND6A
DENN domain containing 6A.
      
 0.478
TTF2
Transcription termination factor 2.
      
 0.457
DNMBP
Dynamin-binding protein; Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions in epithelial cells (By similarity). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a key role in ciliogenesis and cyst formation. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity).
      
 0.455
ZACN
Zinc-activated ligand-gated ion channel; Zinc-activated ligand-gated ion channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
 
   0.426
LOC478649
5-hydroxytryptamine receptor 3D; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
 
   0.422
ENTHD1
ENTH domain containing 1.
      
 0.407
C2CD6
C2 calcium dependent domain containing 6.
  
     0.406
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.