STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC5Uncharacterized protein. (1627 aa)    
Predicted Functional Partners:
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 
 0.911
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 
 0.910
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
   
 
 0.892
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
    
 
 0.849
MUS81
MUS81 structure-specific endonuclease subunit.
    
 
 0.848
CCNH
Cyclin H; Belongs to the cyclin family.
    
 
 0.834
GTF2H1
General transcription factor IIH subunit 1.
    
 
 0.815
XPA
XPA, DNA damage recognition and repair factor.
    
 
 0.809
CDK7
Cyclin dependent kinase 7.
    
 
 0.800
FANCM
FA complementation group M.
   
 
 0.797
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.